Puppy & Dog Vaccinations: Essential Life Stage Schedule
Dog vaccinations are critical to ensuring your four-legged friend stays healthy from puppyhood into their senior years. Vaccines are the safest and most cost-effective way to protect your dog from many infectious preventable diseases.
Apr 2, 2025

Puppy & Dog Vaccinations: Essential Life Stage Schedule
Dog vaccinations are critical to ensuring your four-legged friend stays healthy from puppyhood into their senior years. Vaccines are the safest and most cost-effective way to protect your dog from many infectious preventable diseases. The science behind canine vaccinations has progressed significantly over the past decade, enhancing both their safety and efficacy against existing and emerging pathogens. Here’s why vaccinating a dog is important.
What Are the Common Dog Vaccinations?
Dog vaccinations are split into two general categories: core vaccines and lifestyle vaccines.
Core Vaccines
- Canine distemper/adenovirus-2 (hepatitis)/parvovirus/parainfluenza vaccine (given as one vaccine and commonly referred to as DA2PP, DHPP, or DAPP)
- Rabies virus vaccine
- Leptospira (Leptospirosis) vaccine (this can also be given in combination with the DA2PP/DAPP vaccine, as the DHLPP vaccine)
Lifestyle Vaccines
Lifestyle vaccines are considered optional and given based on factors such as your pet’s lifestyle and where you live. Several lifestyle vaccines protect against highly contagious or potentially life-threatening diseases. To determine which lifestyle vaccines are appropriate for your dog, your vet will look at a variety of factors, including:
- Geographic location and risk of disease in these areas
- Whether your pet goes to doggy day care, dog parks, or boarding or grooming facilities
- Your pet’s lifestyle, including traveling, going on hikes, or being exposed to the wilderness
- The overall health of your pet
Lifestyle vaccines include:
- Bordetella bronchiseptica (kennel cough) vaccine
- Borrelia burgdorferi (Lyme) vaccine
- H3N2/H3N8 (canine influenza) vaccines
- Crotalux atrox (rattlesnake) vaccine
Puppy Vaccine Schedule
For puppy vaccines to provide necessary protection, they’re given every two to four weeks until a puppy is at least 16 weeks old. Certain breeds and puppies in high-risk areas may benefit from receiving the last vaccines at around 18–20 weeks old. Here’s an example of what a typical puppy shot schedule looks like:
| Age | Core Vaccines | Lifestyle Vaccines |
|---|---|---|
| 6–8 weeks | DAP* | Bordetella |
| 10–12 weeks | DHLPP | Lyme, Canine influenza |
| 14–16 weeks | DHLPP, Rabies* |
Lyme, Canine influenza |
*DHP or DHPP if parainfluenza is included, or DHLPP when Leptospirosis is included.
Ultimately, it’s important to consult with your veterinarian to identify the appropriate schedule for puppy vaccines for your specific pet.
Adult Dog Vaccine Schedule
Adult dogs need their core vaccines in addition to any lifestyle vaccines decided upon between you and your veterinarian. A dog vaccination schedule for an adult dog may look like this:
| Frequency | Core Vaccines | Lifestyle Vaccines |
|---|---|---|
| Annual vaccines for dogs | Rabies (initial vaccine), Leptospirosis |
Lyme, Canine influenza, Bordetella (sometimes given every six months) |
| Every three years | DAP, Rabies* |
No three-year lifestyle vaccines available |
*After the initial vaccine, given every three years.
Your veterinarian will determine how long a vaccine will work for your pet. If your dog is overdue or if it’s their first time getting a vaccine, your vet may recommend a booster vaccine or an annual schedule.
What Diseases Do Dog Vaccines Prevent?
Keeping up with your dog vaccinations is the best way to protect your pup from many different illnesses, including:
- Rabies: A fatal neurologic disease transmissible to humans.
- Distemper: Affects respiratory, gastrointestinal, and nervous systems.
- Adenovirus (Hepatitis): Causes liver and kidney failure.
- Parvovirus: Highly contagious, leading to severe gastrointestinal issues.
- Leptospirosis: Can lead to liver or kidney failure and is transmissible to humans.
- Bordetella (Kennel Cough): Causes persistent cough, sometimes severe.
- Lyme Disease: Tick-borne disease causing joint pain and fatigue.
- Canine Influenza: Virus causing respiratory issues.
Which Dog Vaccines Does My Pet Need?
It’s important to discuss your dog’s lifestyle with your veterinarian so they can make appropriate recommendations. Apart from the necessary core vaccines, there is no one-size-fits-all protocol for vaccinating your dog, making your vet's guidance essential.
How Much Do Dog and Puppy Vaccines Cost?
Puppy and dog vaccine costs may vary. Typically, the basic DHLPP vaccine can cost $20–$60 per shot, while the rabies vaccine may be $20–$30. Other non-core vaccines can vary but are generally less than $100 per shot. Vaccines are an essential part of care, important to budget for.
Local shelters or humane societies may offer low-cost or free vaccine clinics. Pet insurance with wellness or preventative care plans can also help offset these costs.
Can Pets Have Adverse Reactions to Vaccines?
Dogs can have mild reactions such as swelling or lethargy. Rarely, severe reactions like anaphylaxis can occur and require immediate vet attention. Monitoring your pet after vaccination is crucial, and past reactions should be reported to your vet.
Puppy and Dog Vaccines FAQs
- How many vaccines does a dog need? This depends on the age, lifestyle, risk factors, and location. Consult with your vet.
- What happens if your dog is not vaccinated? They're susceptible to preventable diseases that can be expensive to treat or fatal.
- Is it ever too late to vaccinate my dog? No, even older dogs should get vaccinated.
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